Others titles

  • New DDD Code 2019
  • New ATC Update and Alterations
  • New DDD Updates and Alterations

Keywords

  • ATC Classification
  • ATC/DDD
  • ATC Alterations
  • DDD Alterations
  • New ATC
  • New DDD

Anatomical Therapeutic Chemical Codes 2018 to 2019

This dataset contains the Anatomical Therapeutic Chemical (ATC) classification system. In ATC the active substances are divided into different groups according to the organ or system on which they act and their therapeutic, pharmacological and chemical properties.

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Description

Drugs are classified in groups at five different levels. The drugs are divided into fourteen main groups (1st level), with pharmacological/therapeutic subgroups (2nd level). The 3rd and 4th levels are chemical/pharmacological/therapeutic subgroups and the 5th level is the chemical substance. The 2nd, 3rd and 4th levels are often used to identify pharmacological subgroups when that is considered more appropriate than therapeutic or chemical subgroups.

The complete classification of metformin illustrates the structure of the code:
– A : Alimentary tract and metabolism (1st level, anatomical main group)
– A10: Drugs used in diabetes (2nd level, therapeutic subgroup)
– A10B: Blood glucose lowering drugs, excl. insulins (3rd level, pharmacological subgroup)
– A10BA: Biguanides (4th level, chemical subgroup)
– A10BA02: metformin (5th level, chemical substance)

Thus, in the ATC system all plain metformin preparations are given the code A10BA02.

Inclusion and exclusion criteria:
The WHO Collaborating Centre in Oslo establishes new entries in the ATC classification on requests from the users of the system. These include manufacturers, regulatory agencies and researchers. The coverage of the system is not comprehensive. A major reason why a substance is not included is that no request has been received.

Active ingredients which fulfill one of the following criteria will normally be included in the ATC system.
– they are new chemical entities (active ingredients) or biologicals proposed for licensing in a range of countries. A new chemical entity is normally not included in the ATC system before an application for marketing authorization is submitted in at least one country.
– they are existing well defined chemical entities used in a variety of countries. An INN should preferably be established for the active ingredient. Alternatively other official names, e.g. USAN or BAN names should be available.
– they are herbal medicinal products assessed and approved by regulatory authorities based on dossiers including efficacy, safety, and quality data (e.g. the well-established use procedure in EU).
Other medicinal products are considered on a case by case basis. Complementary, homeopathic and herbal traditional medicinal products are in general not included in the ATC system.

General principles for classification:
Medicinal products are classified according to the main therapeutic use of the main active ingredient, on the basic principle of only one ATC code for each route of administration (i.e. pharmaceutical forms with similar ingredients and strength will have the same ATC code).

Immediate and slow release tablets will normally have the same ATC code.
A medicinal product can be given more than one ATC code if it is available in two or more strengths or routes of administration with clearly different therapeutic uses. Two examples of this are as follows:
– Sex hormones in certain dosage forms or strengths are only used in the treatment of cancer and are thus classified under L02 – Endocrine therapy. Remaining dosage forms/strengths are classified under G03 – Sex hormones and modulators of the genital system.
– Clonidine is available in two different strengths. One strength, which is used mainly in the treatment of hypertension, is classified under C02 – Antihypertensives. Another strength is mainly used in the treatment of migraine and is classified under N02C – Antimigraine preparations.

About this Dataset

Data Info

Date Created

2017

Last Modified

2017-11-28

Version

2017-11-28

Update Frequency

Semiannual

Temporal Coverage

2018-2019

Spatial Coverage

United States

Source

John Snow Labs; WHO Collaborating Centre for Drug Statistics Methodology;

Source License URL

Source License Requirements

N/A

Source Citation

N/A

Keywords

ATC Classification, ATC/DDD, ATC Alterations, DDD Alterations, New ATC, New DDD

Other Titles

New DDD Code 2019, New ATC Update and Alterations, New DDD Updates and Alterations

Data Fields

Name Description Type Constraints
ATC_CodeA Unique Alpha Numeric Anatomical Therapeutic Chemical Codestring-
ATC_Level_NameAnatomical Therapeutic Chemical Code Level Namestring-

Data Preview

ATC CodeATC Level Name
A02BX14rebamipide
A06AX07plecanatide
A10AE54insulin glargine and lixisenatide
A10BD22metformin and evogliptin
A10BH07evogliptin
A10BJ06semaglutide
A11CC55colecalciferol, combinations
A16AB15velmanase alfa
A16AB16idursulfase beta
A16AB17cerliponase alfa