Defined Daily Dose Alterations 1982 to 2018

$447.50 / year

This dataset contains the DDD (Defined Daily Dose) Alterations from 1982 to 2018.

Complexity

Cumulative overview of all DDD alterations performed in the period 1982-2018. The year changed is when the alterations were implemented in the ATC/DDD Index. Please note that a DDD may have changed more than once for some ATC codes. The ATC codes are current codes. For substances where the DDD is changed twice the new DDD which is not according to the current value is marked with an asterisk (*).

In 1996, WHO recognized the need to develop the use of the ATC/DDD system as an international standard for drug utilization studies. The Centre was therefore linked directly to WHO Headquarters in Geneva instead of the WHO Regional Office for Europe in Copenhagen. This was seen as important to allow close integration of international drug utilization studies and WHO’s initiatives to achieve universal access to needed drugs and rational use of drugs particularly in developing countries. Access to standardized and validated information on drug use is essential to allow audit of patterns of drug utilization, identification of problems, educational or other interventions and monitoring of the outcomes of the interventions.

When the decision on globalizing the ATC/DDD system was taken, the WHO Division of Drug Management and Policies established the WHO International Working Group for Drug Statistics Methodology. The WHO Collaborating Centre for Drug Statistics Methodology receives expert advice from the Working Group.

Date Created

1982

Last Modified

2017-03-23

Version

2017-03-23

Update Frequency

Semiannual

Temporal Coverage

1982-2018

Spatial Coverage

United States

Source

John Snow Labs; WHO Collaborating Centre for Drug Statistics Methodology;

Source License URL

Source License Requirements

N/A

Source Citation

N/A

Keywords

ATC Classification, ATC/DDD, ATC Alterations, DDD Alterations, New ATC, New DDD

Other Titles

New ATC Code 2018, New ATC Update and Alterations, New DDD Updates and Alterations

NameDescriptionTypeConstraints
Substance_NameSubstances Indicated for Rare Disorders with Individual Dosingstring-
Previous_DDDPrevious Rate of Defined Daily Dosenumberlevel : Ratio
Previous_UnitPrevious Unit used for DDD (g = gram, mg milligram, MU = million units, TU = thousand units, U = unit)string-
Previous_Administration_RoutePrevious Administration Route for DDD (N = nasal, Inhal = Inhalation , O = oral, P = parenteral, R = rectal, TD = transdermal, SL = sublingual/buccal)string-
New_DDDNew Rate of Defined Daily Dose. Various Sources are used to get the Best Overview of the Actual or Expected use of a Substance.numberlevel : Ratio
New_UnitNew Unit Used for the New DDD (g = gram, mg milligram, MU = million units, TU = thousand units, U = unit)string-
New_Administration_RouteNew Administration Route for the New DDD (N = nasal, Inhal = Inhalation , O = oral, P = parenteral, TD = transdermal, SL = sublingual/buccal)string-
Present_ATC_CodePresent ATC Codestring-
Year_ChangedYear when DDD was altereddate-
Substance NamePrevious DDDPrevious UnitPrevious Administration RouteNew DDDNew UnitNew Administration RoutePresent ATC CodeYear Changed
Acebutolol0.6gO,P0.4gO,PC07AB041987
Aciclovir1.0gO,P4.0gO,PJ05AB011995
Alosetron2.0mgO1.0mgOA03AE012005
Amoxicillin and enzyme inhibitor1.0gP3.0gPJ01CR022005
ampicillin and enzyme inhibitor2.0gP6.0gPJ01CR012017
Amprenavir2.4gO1.2gOJ05AE052006
Amrinone0.15gP0.5gPC01CE011991
apixaban5.0mgO10.0mgOB01AF022016
Atenolol0.1gO,P75.0mgO,PC07AB031995
Atorvastatin10.0mgO20.0mgOC10AA052009