Earlier this month, it was reported that the Centers for Disease Control and Prevention (CDC) instructed states to sign data use agreements that commit them for the first time to sharing personal information—names, birth dates, ethnicities, and addresses—in existing registries with the federal government. This comes as part of an effort to help us understand more about the spread and efficacy of the newly approved COVID-19 vaccination. As expected, some states are refusing to share this COVID-19 vaccination data information, citing fear that a federal COVID-19 vaccination data registry could be misused or compromised. But at what point does the public health benefit outweigh privacy concerns?