Others titles
- Chemical Vocabulary Chemistry Dictionary
- Chemical Vocabulary Chemistry Terms
- Chemical Vocabulary Chemistry Definition
Keywords
- Toxicogenomics
- Gene Disease Association
- Gene Chemical Pathways
- Gene or Disease Interaction
- Comparative Toxicogenomics Database
- Relationships Between Chemicals and Diseases
- Chemical and Disease Inferences
- Chemical Disease Hypotheses
Chemical Vocabulary
This dataset contains the terms of the vocabulary, organized in a hierarchical manner, used in the Comparative Toxicogenomics Database (CTD) to describe the chemicals inferred to have an interaction over a gene or disease. The dataset contains different types of standardized identifications for the chemical to provide a cross-platform compatibility making able to identify the chemical in major scientific databases.
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Description
The Comparative Toxicogenomics Database (CTD) purpose is to provide a tool to generate new hypotheses on the mechanism of chemicals in the development of diseases by collecting curated data reported in the scientific literature on chemicals, genes and diseases and making inferences on the relationships of these three elements.
The CTD datasets can be used to create a tool for input of queries to obtain inferred relationships between genes, chemicals and diseases and the significance of the inferences. When a query is run, the terms on this dataset are used for input and search of chemicals.
About this Dataset
Data Info
Date Created | 2004-01-20 |
---|---|
Last Modified | 2023-07-28 |
Version | 2023-07 |
Update Frequency |
Monthly |
Temporal Coverage |
N/A |
Spatial Coverage |
N/A |
Source | John Snow Labs; Comparative Toxicogenomics Database; |
Source License URL | |
Source License Requirements |
Publicly available and free for research application but citation is required. Permission asked for commercial uses |
Source Citation |
Publicly available and free for research application but citation is required. Permission asked for commercial uses |
Keywords | Toxicogenomics, Gene Disease Association, Gene Chemical Pathways, Gene or Disease Interaction, Comparative Toxicogenomics Database, Relationships Between Chemicals and Diseases, Chemical and Disease Inferences, Chemical Disease Hypotheses |
Other Titles | Chemical Vocabulary Chemistry Dictionary, Chemical Vocabulary Chemistry Terms, Chemical Vocabulary Chemistry Definition |
Data Fields
Name | Description | Type | Constraints |
---|---|---|---|
Chemical_Name | Name of chemical. | string | required : 1 |
Chemical_ID | Identification number of the chemical by the US National Library of Medicine’s Medical Subject Headings (MeSH). MeSH is a controlled vocabulary of thousands of biomedical terms that serves to standardize the terminology used in published texts that belong to life sciences. Each MeSH term has a unique identifier, which can be from 7 to 8-character length. The MeSH unique identifier was changed to 10-character length after November 2013. | string | required : 1 |
Cas_Registry_Number | Unique numeric identifier designated by CAS for the chemical substance. CAS registry number also serves as a reference to find information on the specific chemical. CAS is a division of the American Chemical Society (ACS); the CAS registry collects information of millions of chemical substances identified since the early 1900’s. | string | - |
Definition | Description of the chemical. | string | - |
Parent_ID | Identifiers of the parent terms ('|'-delimited list). The chemical vocabulary is structured as a polyhierarchic tree in which a chemical may appear as a descendant term in more than one branch, thus belonging to more than one parent term. | string | - |
Tree_Numbers | Identifiers of the nodes where the chemical is located in the tree. ('|'-delimited list) | string | required : 1 |
Parent_Tree_Numbers | Identifiers of the nodes where the parent terms are located in the tree. ('|'-delimited list) | string | - |
Synonyms | Other names by which the chemical is known. ('|'-delimited list) | string | - |
Data Preview
Chemical Name | Chemical ID | Cas Registry Number | Definition | Parent ID | Tree Numbers | Parent Tree Numbers | Synonyms | Drug Bank ID |
(0.017ferrocene)amylose | MESH:C089250 | MESH:D000075163|MESH:D000688|MESH:D005296 | D01.490.200/C089250|D02.691.657/C089250|D09.301.915.361/C089250|D09.698.365.855.361/C089250 | D01.490.200|D02.691.657|D09.301.915.361|D09.698.365.855.361 | (0.017 ferrocene)amylose | |||
001-C8-NBD | MESH:C114385 | MESH:D009842|MESH:D010069 | D03.383.129.462.580/C114385|D12.644.456/C114385 | D03.383.129.462.580|D12.644.456 | 001 C8 NBD|H-MeTyr-Arg-MeArg-D-Leu-NH(CH2)8NH-NBD|MeTyr-Arg-MeArg-Leu-NH-NBD | |||
001-C8 oligopeptide | MESH:C114386 | MESH:D009842 | D12.644.456/C114386 | D12.644.456 | 001 C8 oligopeptide|H-MeTyr-Arg-MeArg-D-Leu-NH(CH2)8NH2 | |||
0231A , Streptomyces | MESH:C434150 | MESH:D006576 | D03.633.400/C434150 | D03.633.400 | ||||
0231B, Streptomyces | MESH:C434149 | MESH:D006576 | D03.633.400/C434149 | D03.633.400 | ||||
027075 compound | MESH:C000620092 | MESH:D010793|MESH:D052117 | D03.383.246.118/C000620092|D03.383.710.605/C000620092|D03.633.100.115/C000620092 | D03.383.246.118|D03.383.710.605|D03.633.100.115 | N-(benzo(d)(1,3)dioxol-5-yl)-2-(1-oxo-4-(p-tolyl)-5,6,7,8-tetrahydrophthalazin-2(1H)-yl)butanamide | |||
0433YC1 | MESH:C533344 | MESH:D006576 | D03.633.400/C533344 | D03.633.400 | ||||
0433YC2 | MESH:C533345 | MESH:D006576 | D03.633.400/C533345 | D03.633.400 | ||||
06-Paris-LA-66 protocol | MESH:C046983 | MESH:D003630|MESH:D008727|MESH:D011239|MESH:D014750 | D02.455.426.559.847.562.050.200/C046983|D03.132.436.681.827.817/C046983|D03.633.100.473.402.681.827.817/C046983|D03.633.100.496.500.500.681.827.817/C046983|D03.633.100.733.631.192.500/C046983|D04.210.500.745.432.769.795/C046983|D04.615.562.050.200/C046983|D09.408.051.059.200/C046983 | D02.455.426.559.847.562.050.200|D03.132.436.681.827.817|D03.633.100.473.402.681.827.817|D03.633.100.496.500.500.681.827.817|D03.633.100.733.631.192.500|D04.210.500.745.432.769.795|D04.615.562.050.200|D09.408.051.059.200 | Paris-LA | |||
071031B compound | MESH:C585814 | MESH:D013876|MESH:D052117 | D02.886.778/C585814|D03.383.246.118/C585814|D03.383.903/C585814|D03.633.100.115/C585814 | D02.886.778|D03.383.246.118|D03.383.903|D03.633.100.115 |