Expression Profiles For Proteins in Normal Human Tissues

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This dataset covers the Expression profiles for proteins in human tissues based on immunohistochemistry using tissue microarrays. The data is based on The Human Protein Atlas version 16 and Ensembl version 83.38.

Complexity

The Expression Profiles For Proteins in Normal Human Tissues contains quantitative data and images describing the expression and distribution of human proteins across tissues and organs, both on the mRNA and protein level. The protein expression data is derived from annotation of immunohistochemical staining of cell populations in all major human tissues and organs, including the brain, liver, kidney, lymphoid tissues, heart, lung, skin, gastrointestinal tract, pancreas, endocrine tissues and the reproductive organs. In total, 44 different human tissues are included and contain annotation data for altogether 76 different cell types. The antibody-based protein profiles are qualitative and describe the spatial distribution, cell type specificity and the rough relative abundance of proteins in these tissues, whereas the mRNA data provide quantitative data on the average gene expression within an entire tissue. For each gene, the immunohistochemical staining profile, based on a single or multiple antibodies, is matched with mRNA data and gene/protein characterization data to yield an “annotated protein expression” profile.

Date Created

2003

Last Modified

2016-12-04

Version

16

Update Frequency

Annual

Temporal Coverage

N/A

Spatial Coverage

United States

Source

John Snow Labs => The Human Protein Atlas, Ensembl

Source License URL

John Snow Labs Standard License

Source License Requirements

Publicly available and free for research application but citation is required. Permission asked for commercial uses

Source Citation

Human Protein Atlas available from www.proteinatlas.org

Keywords

Cell Microarray, Immunohistochemisty, Expression Profiles of Normal Tissues, Expression Profiles for Proteins in Human Tissues, Protein Staining Profiles, Normal Human Tissue, Human Tissue Specimens, Potential Cancer Biomarkers

Other Titles

Gene Expression Based on Immunohistochemistry of Normal Tissue, Expression Profiles for Proteins Using Normal Human Tissues

Name Description Type Constraints
Ensembl_Gene_IDGene ID by Ensemblstringrequired : 1
Gene_IDID assigned to the gene. Each gene has a unique ID.stringrequired : 1
Tissue_NameName of tissue from which protein expression data is derivedstringrequired : 1
Name_of_Cell_TypeName of annotated cell typestringrequired : 1
Levelstringrequired : 1
ReliabilityGene reliability of the expression valuestringrequired : 1
Ensembl_Gene_IDGene_IDTissue_NameName_of_Cell_TypeLevelReliability
ENSG00000135517MIPeyelensHighSupportive
ENSG00000121743GJA3eyelensHighSupportive
ENSG00000146166LGSNeyelensHighSupportive
ENSG00000184887BTBD6eyelensHighUncertain
ENSG00000170819BFSP2eyelensHighSupportive
ENSG00000196431CRYBA4eyelensHighSupportive
ENSG00000244752CRYBB2eyelensHighSupportive
ENSG00000125864BFSP1eyelensMediumSupportive
ENSG00000173599PClungmacrophagesLowUncertain
ENSG00000173599PClungpneumocytesLowUncertain