Others titles
- Gene Expression Based on Immunohistochemistry of Normal Tissue
- Expression Profiles for Proteins Using Normal Human Tissues
Keywords
- Cell Microarray
- Immunohistochemisty
- Expression Profiles of Normal Tissues
- Expression Profiles for Proteins in Human Tissues
- Protein Staining Profiles
- Normal Human Tissue
- Human Tissue Specimens
- Potential Cancer Biomarkers
Expression Profiles For Proteins in Normal Human Tissues
This dataset covers the Expression profiles for proteins in human tissues based on immunohistochemistry using tissue microarrays. The data is based on The Human Protein Atlas version 21.1 and Ensembl version 103.38.
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Description
The Expression Profiles For Proteins in Normal Human Tissues contains quantitative data and images describing the expression and distribution of human proteins across tissues and organs, both on the mRNA and protein level. The protein expression data is derived from annotation of immunohistochemical staining of cell populations in all major human tissues and organs, including the brain, liver, kidney, lymphoid tissues, heart, lung, skin, gastrointestinal tract, pancreas, endocrine tissues and the reproductive organs. In total, 44 different human tissues are included and contain annotation data for altogether 76 different cell types. The antibody-based protein profiles are qualitative and describe the spatial distribution, cell type specificity and the rough relative abundance of proteins in these tissues, whereas the mRNA data provide quantitative data on the average gene expression within an entire tissue. For each gene, the immunohistochemical staining profile, based on a single or multiple antibodies, is matched with mRNA data and gene/protein characterization data to yield an “annotated protein expression” profile.
About this Dataset
Data Info
Date Created | 2003 |
---|---|
Last Modified | 2022-05-30 |
Version | 21.1 |
Update Frequency |
Annual |
Temporal Coverage |
N/A |
Spatial Coverage |
United States |
Source | John Snow Labs; The Human Protein Atlas, Ensembl; |
Source License URL | |
Source License Requirements |
Publicly available and free for research application but citation is required. Permission asked for commercial uses |
Source Citation |
Publicly available and free for research application but citation is required. Permission asked for commercial uses |
Keywords | Cell Microarray, Immunohistochemisty, Expression Profiles of Normal Tissues, Expression Profiles for Proteins in Human Tissues, Protein Staining Profiles, Normal Human Tissue, Human Tissue Specimens, Potential Cancer Biomarkers |
Other Titles | Gene Expression Based on Immunohistochemistry of Normal Tissue, Expression Profiles for Proteins Using Normal Human Tissues |
Data Fields
Name | Description | Type | Constraints |
---|---|---|---|
Ensembl_Gene_ID | Gene ID by Ensembl | string | required : 1 |
Gene_ID | ID assigned to the gene. Each gene has a unique ID. | string | - |
Tissue_Name | Name of tissue from which protein expression data is derived | string | - |
Name_of_Cell_Type | Name of annotated cell type | string | - |
Level | string | - | |
Reliability | Gene reliability of the expression value | string | - |
Data Preview
Ensembl Gene ID | Gene ID | Tissue Name | Name of Cell Type | Level | Reliability |
ENSG00000000003 | TSPAN6 | adipose tissue | adipocytes | Not detected | Approved |
ENSG00000000003 | TSPAN6 | adrenal gland | glandular cells | Not detected | Approved |
ENSG00000000003 | TSPAN6 | appendix | glandular cells | Medium | Approved |
ENSG00000000003 | TSPAN6 | appendix | lymphoid tissue | Not detected | Approved |
ENSG00000000003 | TSPAN6 | bone marrow | hematopoietic cells | Not detected | Approved |
ENSG00000000003 | TSPAN6 | breast | adipocytes | Not detected | Approved |
ENSG00000000003 | TSPAN6 | breast | glandular cells | High | Approved |
ENSG00000000003 | TSPAN6 | breast | myoepithelial cells | Not detected | Approved |
ENSG00000000003 | TSPAN6 | bronchus | respiratory epithelial cells | High | Approved |
ENSG00000000003 | TSPAN6 | caudate | glial cells | Not detected | Approved |