Human and Animal Cell Lines

$79 / year

This dataset consists of a collection of cell lines by DSMZ (Deutsche Sammlung von Mikroorganismen und Zellkulturen Institute). This collection currently comprises more than 800 different immortalized cell cultures of primate, rodent, amphibian, fish, insect origin isolated from numerous tissues and hybridomas.

Complexity

The use of animal cell cultures as models of human disease is an integral part of scientific research, providing taxonomic equivalents resembling human physiology. The study of animal cells also affords researchers greater understanding in areas of developmental biology, protein expression, and genetic evolution.

An immortalized cell line is a population of cells from a multicellular organism which would normally not proliferate indefinitely but, due to mutation, have evaded normal cellular senescence and instead can keep undergoing division. The cells can therefore be grown for prolonged periods in vitro. The mutations required for immortality can occur naturally or be intentionally induced for experimental purposes. Immortal cell lines are a very important tool for research into the biochemistry and cell biology of multicellular organisms.

While developing a new cell line; the following points should be kept in mind
– Record all data relevant to the origin of the tissue when starting a new cell line and keep tissue for DNA profiling.
– Make sure the names of new cell lines are unique.
– Acquired cell lines should come from a reliable source and must be authenticated to avoid misidentification.
– Authenticated cells should be banked for future use and cultures replaced regularly from frozen stock.
– Regulations often apply to the distribution of cell lines and only authenticated stocks should be distributed.

Cell lines can be developed in-house, acquired from other laboratories (if there is no more reliable source) or purchased from a cell bank. Whatever the source, it is essential to ensure that the cells are authenticated and free from contamination such as mycoplasma.

Date Created

2014-10-03

Last Modified

2016

Version

2016

Update Frequency

Irregular

Temporal Coverage

N/A

Spatial Coverage

N/A

Source

John Snow Labs => Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures

Source License URL

John Snow Labs Standard License

Source License Requirements

N/A

Source Citation

N/A

Keywords

Cell Line, Genetic Cell Lines, List of Cell Lines, Human and animanl cell lines, Animal Cell Cultures as Models, Animal Cell Cultures, Animal Cell as Models, Immortalized Cell Line

Other Titles

List of Cell Lines From Human and Animal Species, Animal and Human Cell Line Catalog

Name Description Type Constraints
Cell_Line_IDCell Line Identifier by DSMZ (Deutsche Sammlung von Mikroorganismen und Zellkulturen Institute)string-
DSMZ_Cell_Line_NumberCell Line Number assigned by DSMZintegerrequired : 1 level : Nominal
Nonstandard_Species_NameSpecies name from which the cell line sample is takenstringrequired : 1
Name_of_Cell_TypeName of the cell type based on differential regulation of the genes they contain.string-
Cell_Line_IDDSMZ_Cell_Line_NumberNonstandard_Species_NameName_of_Cell_Type
C6550ratglioma
XC118ratsarcoma
GAMG242humanglioma
MH1C1106rathepatoma
DK-MG277humanglioma
JTC-15329rathepatoma
JTC-27330rathepatoma
MEL-HO62humanmelanoma
A-S-30D208rathepatoma
IGR-1236humanmelanoma