Pharmacology Mapping of Target ID and UniProt Accessions

$79 / year

This dataset shows the Target Identification and UniProt Accessions from the Guide to PHARMACOLOGY; an online, open-access portal to pharmacological information on all the human targets of prescription drugs, which is the product from the collaboration of the International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS).

Complexity

The data types captured in this dataset include target nomenclature, pharmacological data, and ligand structures. Organisms isolated in this data are from human, mouse, and rat.

In future versions, the plan is to add resources for education and training in pharmacological principles and techniques along with research guidelines and overviews of key topics. It is the hope of IUPHAR/BPS Guide to PHARMACOLOGY to be useful for researchers and students in pharmacology and drug discovery and provide the general public with accurate information on the basic science underlying drug action.

The information provided in this dataset shows the initial view or landing pages for each target family that provides expert-curated overviews of the key properties and selective ligands and tool compounds available. Additional information can be found also in other databases including Ensembl, UniProt, PubChem, ChEMBL, and DrugBank, as well as curated chemical information and literature citations in PubMed.

Date Created

2011

Last Modified

2017-04-24

Version

2017.3

Update Frequency

Quarterly

Temporal Coverage

N/A

Spatial Coverage

N/A

Source

John Snow Labs => International Union of Basic and Clinical Pharmacology (IUPHAR) and the British Pharmacological Society (BPS) Guide to PHARMACOLOGY

Source License URL

John Snow Labs Standard License

Source License Requirements

N/A

Source Citation

Southan C, Sharman JL, Benson HE, Faccenda E, Pawson AJ, Alexander SPH, Buneman OP, Davenport AP, McGrath JC, Peters JA, Spedding M, Catterall WA, Fabbro D, Davies JA; NC-IUPHAR. (2016) The IUPHAR/BPS Guide to PHARMACOLOGY in 2016 towards curated quantitative interactions between 1300 protein targets and 6000 ligands. Nucl. Acids Res. 44 (Database Issue) D1054-68

Keywords

NCBI Gene, Entrez Gene, NCBI Protein, Protein Database, Proteome, National Center for Biotechnology Information

Other Titles

Pharmacology NCBI Gene Identification and UniProt Accessions, Pharmacology NCBI Protein Identification and UniProt Accessions, Pharmacology Protein Database and UniProt Accessions, Pharmacology Proteome Identification and UniProt Accessions

Name Description Type Constraints
Uniprot_IdThe UniProtKB/SwissProt Accession for the protein sequencestringrequired : 1
SpeciesThe common name of the speciesstringrequired : 1
Iuphar_NameThe GtP target name, usually the International Union of Basic and Clinical Pharmacology (IUPHAR) recommended a name or a provisional name (for information on target nomenclature see the online help documentation)stringrequired : 1
Iuphar_IdThe GtP International Union of Basic and Clinical Pharmacology (IUPHAR) target identifierintegerrequired : 1 level : Nominal
Gtp_UrlThe GtP (guanosine triphosphate) target page URLstringrequired : 1
Uniprot_IdSpeciesIuphar_NameIuphar_IdGtp_Url
Q9JLY8RatCCR158http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=58
O55193RatCCR259http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=59
O54814RatCCR360http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=60
O08556RatCCR562http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=62
Q5BK58RatCCR663http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=63
Q6U2D6RatCCR764http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=64
Q8CH33RatCCR966http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=66
O89039RatACKR380http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=80
D3ZVM9RatCCRL278http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=78
Q9JMD7RatCHT914http://www.guidetopharmacology.org/GRAC/ObjectDisplayForward?objectId=914