Aspirin or Clopidogrel Early VS Delayed Treatment in Hip Fractures

$79 / year

This dataset showcases the limited evidence that supports not delaying hip fracture surgery for patients on aspirin and/or clopidogrel.

Complexity

Previously, some surgeons have delayed surgery for hip fracture patients on Aspirin and/or clopidogrel. This systematic review suggests at worse that there is no advantage to this practice or that in fact, the advantage is for patients where surgery is not delayed. The benefit of implementing this recommendation is preventing an unnecessary (unhelpful) delay in performing hip fracture surgery.

As with all surgical procedures, there are potential risks and complications, including, but not limited to, the possibility of bleeding. There is no data suggesting patient outcome harms will occur with the implementation of this recommendation.

Date Created

2014-09-05

Last Modified

2014-09-05

Version

2014-09-05

Update Frequency

Never

Temporal Coverage

2003-2013

Spatial Coverage

United States

Source

John Snow Labs => American Academy of Orthopaedic Surgeons (AAOS)

Source License URL

John Snow Labs Standard License

Source License Requirements

N/A

Source Citation

N/A

Keywords

Hip Fractures, Aspirin or Clopidogrel Treatment, Early Versus Delayed Treatment for Hip Fractures, Treatment for Hip Fractures, General Anesthesia for Hip Fractures in the Elderly, Anesthesia for Hip Fractures, Fractures in the Elderly, Clopidogrel Side Effects, Antiplatelet Drugs for Fracture, Antiplatelet Therapy

Other Titles

Aspirin or Clopidogrel Treatment in the Management of Hip Fractures, AAOS Guidelines on Hip Fracture Management, Early Versus Delayed Drug Treatment for Hip Fractures, Aspirin or Clopidogrel Side Early Versus Delayed Treatment in Elderly Hip Fractures, Antiplatelet Drug Aspirin or Clopidogrel Early Versus Delayed Treatment in Elderly Hip Fractures, Antiplatelet Therapy Aspirin or Clopidogrel Early Versus Delayed Treatment in Elderly Hip Fractures

Name Description Type Constraints
StudyDescription of the previous studies used in this research.stringrequired : 1
OutcomeDescription of the reported outcomes from the participants who received Aspirin or Clopidogrel whether early or delayed treatment is used for the research study.stringrequired : 1
DurationDescription of the duration of the effect of Aspirin or Clopidogrel whether early or delayed.stringrequired : 1
Group_1Description of the treatment used in the first group.stringrequired : 1
Group_2Description of the treatment used in the second group.stringrequired : 1
Population_SizeShows the number of participants or population size in a certain group that received Aspirin or Clopidogrel whether early or delayed.integerrequired : 1 level : Ratio
StatisticDescription of the measurable characteristic of a sample population.stringrequired : 1
ResultResults of the study.numberrequired : 1 level : Ratio
ProbabilityEffectiveness of the result based on the hypothesis of the study.string-
Study_P_ValueStatistical significance of the results of the study.string-
FavorsDescription of which method is more effective.stringrequired : 1
StudyOutcomeDurationGroup_1Group_2Population_SizeStatisticResultProbabilityStudy_P_ValueFavors
Thaler et al 2010MortalityUnclearAspirin no delayNo platelet inhibitors, no delay440Risk ratio0.860.81NS
Manning et al 2003Require blood transfusion24 hoursAspirinNo aspirin89Risk ratio2.140.04Favors no aspirin
Thaler et al 2010Major BleedingUnclearAspirin no delayNo platelet inhibitors, no delay440Risk ratio0.860.81NS
Chechik et al 2012Complication: CVA12Clopidogrel, early treatmentClopidogrel, delayed treatment60Risk ratio11NS
Chechik et al 2012Complication: ACS12Clopidogrel, early treatmentClopidogrel, delayed treatment60Risk ratio30.33NS
Thaler et al 2010Blood drainage (ml)UnclearAspirin no delayNo platelet inhibitors, no delay440Mean difference10.98NS
Thaler et al 2010MortalityIn hospitalClopidogrelno delayNo platelet inhibitors, no delay364% Risk difference2.90.378NS
Chechik et al 2012Complication: Pneumonia12Clopidogrel, early treatmentClopidogrel, delayed treatment60Risk ratio20.4NS
Thaler et al 2010Major BleedingUnclearClopidogrelno delayNo platelet inhibitors, no delay364% Risk difference2.90.378NS
Chechik et al 2012Complication: Sepsis12Clopidogrel, early treatmentClopidogrel, delayed treatment60Risk ratio0.670.64NS