- What are Genetics?
- Genomic Testing Associated With Longevity
- Genetic Testing Associated With Longevity
- Longevity Map
- Human Longevity
- Longevity Gene
- Longevity Study
- Genetic Association
Human Genetic Variants Associated With LongevityMap
This dataset is a manually curated database of genetic association studies of longevity and reflects current knowledge of the genetics related to human longevity.
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This dataset comes from The Human Ageing Genomic Resources (HAGR), a repository containing information about the genetics of human aging. Information is obtained from modern approaches such as functional genomics, network analyses, systems biology and evolutionary analyses.
The dataset “Human Genetic Variants Associated With Longevity” is a list of human genetic variants (e.g., SNPs), genes and their chromosomal locations showing the diversity of human genetic association studies of longevity. All entries in this list are manually curated from the literature. Studies were selected following a rigorous literature survey that excluded studies in cohorts of unhealthy individuals at baseline. Both large and small studies are included, including population.
Negative results are also included in the list to provide as much information as possible regarding each gene and variant previously studied in the context of longevity. Each entry refers to a specific observation from a study and is flagged whether results were or not statistically significant. Large-scale studies often have multiple entries in this list. The present list features 551 manually-curated entries, 860 genes and 3025 genetic variants.
About this Dataset
John Snow Labs; Human Ageing Genomic Resources;
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Budovsky, A., Craig, T., Wang, J., Tacutu, R., Csordas, A., Lourenco, J., Fraifeld, V. E., de Magalhaes, J. P. (2013) "LongevityMap A database of human genetic variants associated with longevity." Trends in Genetics 29559-560.
Aging, Longevity, Longevity Map, Human Longevity, Longevity Gene, SNP, Longevity Study, Genetic Association
What are Genetics?, Genomic Testing Associated With Longevity, Genetic Testing Associated With Longevity
|Id||Entry number with individual genes starting with single integer digits. Entries with "G" prefix are entries with multiple genes/variants.||string||unique : 1required : 1|
|Population_Type||Type of human population (depending on the geographical region of the world) under study||string||required : 1|
|Association||Each entry refers to a specific observation from a study and is flagged whether results were or not statistically significant after accessing genetic association with longevity.||string||-|
|Genes||Gene symbol of the gene associated with a longevity or gene studied||string||-|
|Genetic_Variants||Type of genetic variation studied in that particular study. Genetic variants can be single nucleotide polymorphism (SNP) represented by either their "rs" number or position followed by reference/alternate allele, insertion "INS (reference allele) position(alternate allele)" or mitochondrial DNA variations represented by "Mt (reference allele) position (alternate allele)".||string||-|
|PubMed_Id||Pubmed ID numbers from the NCBI website for referring the article||string||required : 1|