Others titles
- Gene Expression Based on Immunohistochemistry of Cancer Tissue
- Expression Profiles for Proteins Using Cancer Tissues
Keywords
- Protein Staining Profiles
- Human Tumor Tissue
- Human Cancer Specimens
- Potential Cancer Biomarkers
- Tissue Microarray Data
- Immunohistochemistry
- Expression profiles of cancer tissues
Expression Profiles For Proteins in Human Cancer Tissues
This dataset covers the staining profiles for proteins in human tumor tissue based on immunohistochemistry using tissue microarrays. The data is based on The Human Protein Atlas version 21.0 and Ensembl version 103.38.
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Description
The cancer tissue dataset contains a multitude of human cancer specimens representing the 20 most common forms of cancer, including breast-, colon-, prostate-, lung-, urothelial-, skin-, endometrial- and cervical cancer. Altogether 216 different cancer samples are used to generate protein expression profiles for all proteins using immunohistochemistry. The data is presented as pathology-based annotation of protein expression levels in tumor cells, along with the images underlying the annotation. This enables the identification of a potential protein signature for each given type of cancer and provides a starting point for further analyses of cancer type-specific proteins. Because the cancer atlas contains a large number of cancer samples the available protein profiles provide an excellent starting point for identifying new potential cancer biomarkers.
About this Dataset
Data Info
Date Created | 2003 |
---|---|
Last Modified | 2022-05-30 |
Version | 21.1 |
Update Frequency |
Annual |
Temporal Coverage |
N/A |
Spatial Coverage |
United States |
Source | John Snow Labs; The Human Protein Atlas, Ensembl; |
Source License URL | |
Source License Requirements |
Publicly available and free for research application but citation is required. Permission asked for commercial uses |
Source Citation |
Publicly available and free for research application but citation is required. Permission asked for commercial uses |
Keywords | Protein Staining Profiles, Human Tumor Tissue, Human Cancer Specimens, Potential Cancer Biomarkers, Tissue Microarray Data, Immunohistochemistry, Expression profiles of cancer tissues |
Other Titles | Gene Expression Based on Immunohistochemistry of Cancer Tissue, Expression Profiles for Proteins Using Cancer Tissues |
Data Fields
Name | Description | Type | Constraints |
---|---|---|---|
Ensembl_Gene_ID | Gene ID by Ensembl | string | required : 1 |
Gene_ID | Name assigned to gene. | string | required : 1 |
Tumor_Name | Name of Tumor tissue | string | required : 1 |
Level_of_Staining_High | Staining value for high level of staining | integer | level : Ratio |
Level_of_Staining_Medium | Staining value for medium level of staining | integer | level : Ratio |
Level_of_Staining_Low | Staining value for low level of staining | integer | level : Ratio |
Level_of_Staining_Not_Detected | Staining value for the level of staining not detected | integer | level : Ratio |
P_Values_For_Patient_Survival_For_Prognostic_Favorable | Log-rank p values for patient survival and mRNA correlation for prognostic favorable. | string | - |
P_Values_For_Patient_Survival_For_Unprognostic_Favorable | Log-rank p values for patient survival and mRNA correlation for unprognostic favorable. | string | - |
P_Values_For_Patient_Survival_For_Prognostic_Unfavorable | Log-rank p values for patient survival and mRNA correlation for prognostic unfavorable. | string | - |
P_Values_For_Patient_Survival_For_Unprognostic_Unfavorable | Log-rank p values for patient survival and mRNA correlation for unprognostic unfavorable. | string | - |
Data Preview
Ensembl Gene ID | Gene ID | Tumor Name | Level of Staining High | Level of Staining Medium | Level of Staining Low | Level of Staining Not Detected | P Values For Patient Survival For Prognostic Favorable | P Values For Patient Survival For Unprognostic Favorable | P Values For Patient Survival For Prognostic Unfavorable | P Values For Patient Survival For Unprognostic Unfavorable |
ENSG00000000003 | TSPAN6 | breast cancer | 1 | 7 | 2 | 2 | 0.0771 | |||
ENSG00000000003 | TSPAN6 | carcinoid | 0 | 1 | 1 | 2 | ||||
ENSG00000000003 | TSPAN6 | cervical cancer | 11 | 1 | 0 | 0 | 0.0897 | |||
ENSG00000000003 | TSPAN6 | colorectal cancer | 0 | 6 | 2 | 2 | 0.0356 | |||
ENSG00000000003 | TSPAN6 | endometrial cancer | 10 | 2 | 0 | 0 | 0.257 | |||
ENSG00000000003 | TSPAN6 | glioma | 0 | 0 | 0 | 11 | 0.00271 | |||
ENSG00000000003 | TSPAN6 | head and neck cancer | 0 | 3 | 1 | 0 | 0.0593 | |||
ENSG00000000003 | TSPAN6 | liver cancer | 4 | 5 | 1 | 0 | 0.10400000000000001 | |||
ENSG00000000003 | TSPAN6 | lung cancer | 8 | 4 | 0 | 0 | 0.0109 | |||
ENSG00000000003 | TSPAN6 | lymphoma | 0 | 0 | 0 | 11 |